Search results for " Continuous positive airway pressure"

showing 10 items of 15 documents

Diagnostic and Therapeutic Approach to Sleep Disorders, High Blood Pressure and Cardiovascular Diseases. A Consensus Document by the Italian Society …

2021

Hypertension is a major contributor to fatal/nonfatal cardiovascular diseases, and timely identification and appropriate management of factors affecting hypertension and its control are mandatory public health issues. By inducing neurohormonal alterations and metabolic impairment, sleep disorders have an impact on a variety of cardiovascular risk factors, including hypertension, and ultimately increase the risk of cardiovascular events. There is evidence that qualitative and quantitative sleep disorders are associated with resistant hypertension and with impaired circadian blood pressure variations. However, sleep disturbances are often unrecognized, or heterogeneity exists in their managem…

0301 basic medicinemedicine.medical_treatmentSleep disorders.Comorbidity0302 clinical medicineCardiovascular DiseaseSleep Initiation and Maintenance DisordersInsomniaContinuous positive airway pressureSleep Apnea ObstructiveContinuous Positive Airway Pressureblood pressureHeart Disease Risk FactorPrognosisSleep in non-human animalsCircadian RhythmAntihypertensive AgentCardiovascular Diseasessleep disordersmedicine.symptomCardiology and Cardiovascular MedicineRisk assessmentHumancardiovascular riskmedicine.medical_specialtyConsensusSleep ApneahypertensionPrognosiConsensuRisk Assessment03 medical and health sciencesTherapeutic approachInternal MedicinemedicineHumansHealthy LifestyleIntensive care medicineConsensus DocumentAntihypertensive AgentsBlood pressure; Cardiovascular risk; Hypertension; Sleep disorders; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Circadian Rhythm; Comorbidity; Consensus; Healthy Lifestyle; Heart Disease Risk Factors; Humans; Hypertension; Prognosis; Risk Assessment; Risk Reduction Behavior; Sleep Apnea Obstructive; Sleep Initiation and Maintenance Disorders; Continuous Positive Airway Pressure; SleepSleep disorderbusiness.industryObstructivePublic healthmedicine.diseaseComorbidity030104 developmental biologyBlood pressureHeart Disease Risk Factorsblood pressure; cardiovascular risk; hypertension; sleep disordersbusinessSleepRisk Reduction Behavior030217 neurology & neurosurgery

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Do ventilatory parameters influence outcome in patients with severe acute respiratory infection? Secondary analysis of an international, multicentre1…

2021

Purpose: To investigate the possible association between ventilatory settings on the first day of invasive mechanical ventilation (IMV) and mortality in patients admitted to the intensive care unit (ICU) with severe acute respiratory infection (SARI). Materials and methods: In this pre-planned sub-study of a prospective, multicentre observational study, 441 patients with SARI who received controlled IMV during the ICU stay were included in the analysis. Results: ICU and hospital mortality rates were 23.1 and 28.1%, respectively. In multivariable analysis, tidal volume and respiratory rate on the first day of IMV were not associated with an increased risk of death; however, higher driving pr…

ARDSSoins intensifs réanimationmedicine.medical_treatmentAirway pressuresPEEP positive end-expiratory pressureCritical Care and Intensive Care Medicinelaw.inventionHypoxemiaCohort StudiesPositive-Pressure RespirationMechanical ventilationSARI severe acute respiratory infectionlawHospital MortalityProspective StudiesIQR interquartile rangesProspective cohort studyRCT randomized controlled trialTidal volumeSOFA Sequential Organ Failure AssessmentSAPS Simplified Acute Physiology ScoreIntensive care unitVCV volume-controlled ventilationHIV human immunodeficiency virusIntensive Care UnitsIC GLOSSARI Intensive Care Global Study on Severe Acute Respiratory Infectionmedicine.symptomCohort studyLOS length of staymedicine.medical_specialtyVt tidal volumeCOPD Chronic obstructive pulmonary diseaseNYHA New York Heart Association.PCV pressure-controlled ventilationArticleInternal medicineICU Intensive Care UnitSIMV Synchronized intermittent mandatory ventilationmedicineTidal VolumeHumansDP driving pressurePEEPARDS acute respiratory distress syndromeMechanical ventilationbusiness.industryOdds ratioPneumoniaPlateau pressuremedicine.diseaseRespiration ArtificialVILI ventilator induced lung injuryCI confidence intervalOR odds ratioIMV invasive mechanical ventilationCPAP continuous positive airway pressureARDSbusinessSD standard deviationECMO extracorporeal membrane oxygenationPBW predicted body weightPplat plateau pressure

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Sleep apnoea and systemic hypertension

2010

Anti-hypertensive treatment cardiovascular risk continuous positive airway pressure treatment pathophysiology.Settore MED/10 - Malattie Dell'Apparato Respiratorio

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Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review

2020

Abstract Background Tocilizumab is an IL-6 receptor-blocking agent proposed for the treatment of severe COVID-19. The aim of this systematic review was to describe the rationale for the use of tocilizumab for the treatment of COVID-19 and to summarize the available evidence regarding its efficacy and safety. Methods MEDLINE, PubMed, EMBASE, pre-print repositories (bioRxiv and medRxiv) and two trial Registries were searched for studies on the use of tocilizumab in COVID-19 or SARS-CoV-2 infection, viral pneumonia, and/or sepsis until 20th June 2020. Results We identified 3 indirect pre-clinical studies and 28 clinical studies including 5776 patients with COVID-19 (13 with a comparison group,…

Coronavirus COVID-19 Pneumonia SARS-CoV-2 TocilizumabGCA Giant cell arteritispJIA Pediatric juvenile idiopathic arthritislaw.inventionchemistry.chemical_compound0302 clinical medicineRandomized controlled triallawMedicine030212 general & internal medicineClinical efficacyCPAP Continuous positive airway pressureCOVID-19 Coronavirus disease 2019IDSA Infectious Diseases Society of AmericaRA Rheumatoid arthritisTocilizumabIMV Invasive mechanical ventilationsJIA Juvenile idiopathic arthritisAIFA Agenzia Italiana del FarmacoPulmonary and Respiratory Medicinemedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MEDLINEAntibodies Monoclonal HumanizedNIH U.S. National Institutes of HealthArticleWHO World Health OrganizationSIMIT Italian Society of Infectious and Tropical disease03 medical and health sciencesTocilizumabARDS Acute respiratory distress syndromeAnimalsHumansIn patientIntensive care medicineTocilizumab ; COVID-19 ; Pneumonia ; SARS-CoV-2 ; Coronaviruslcsh:RC705-779business.industryCRS CAR-T cell-induced cytokine release syndromeInterleukin-6SARS-CoV-2NIV Noninvasive mechanical ventilationTNF Tumor necrosis factorCOVID-19Pneumonialcsh:Diseases of the respiratory systemCOVID-19 Drug TreatmentClinical trialCoronavirus030228 respiratory systemchemistrybusinessICTRP International Clinical Trials Registry PlatformPulmonology

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N-BiPAP vs n-CPAP in term neonate with respiratory distress syndrome

2020

Abstract Background Non-invasive respiratory ventilation has greatly improved the evolution of respiratory distress in neonates, especially for preterm infants, but few studies have investigated the use of non-invasive ventilation (NIV) in term infants. It is useful for neonatologists and nurses to identify the optimal ventilation strategy in terms of effectiveness for this group of newborns. The aim of our study was to investigate what type of respiratory support between nasal Continuous Positive Airway Pressure (nCPAP) or nasal Biphasic Positive Airway Pressure (nBiPAP) is more effective in term neonates with RDS. Methods Our study was a retrospective observational study of 78 full term n…

MaleTerm infantsRespiratory distress syndromemedicine.medical_treatmentContinuous positive airway pressureVital signsBiphasic positive airway pressureNOBiphasic Positive Airway PressurePositive-Pressure Respiration03 medical and health sciences0302 clinical medicine030225 pediatricsmedicineHumansBiphasic positive airway pressure; Continuous positive airway pressure; Non-invasive ventilation; Respiratory distress syndrome; Term infants;Continuous positive airway pressureRespiratory systemFull TermRespiratory Distress Syndrome NewbornNoninvasive VentilationRespiratory distressbusiness.industryInfant NewbornObstetrics and Gynecologyrespiratory systemmedicine.diseaseBiphasic positive airway pressure; Continuous positive airway pressure; Non-invasive ventilation; Respiratory distress syndrome; Term infantsTerm infants.PneumothoraxAnesthesiaPediatrics Perinatology and Child HealthNon-invasive ventilationBreathingFemalebusiness030217 neurology & neurosurgeryEarly Human Development

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Perioperative Adverse Events in Obstructive Sleep Apnea and Use of Noninvasive Mechanical Ventilation: Key Topics and Clinical Implications

2016

Obstructive sleep apnea (OSA) is a common public health care problem and, yet, the perioperative management of OSA remains inadequate. Patients affected by this condition are prone to early postoperative complications, in part due to the negative effects of sedative, analgesic, and anesthetic agents on pharyngeal tone and arousal responses to hypoxia, hypercapnia, and obstruction. The use of opioids may also contribute to late adverse events, mainly by suppressing the rapid eye movement phase of sleep. As a result, preoperative screening of patients at high risk of OSA, as well as the implementation of a perioperative strategy to reduce the risk of complications, should lead to early periop…

Mechanical ventilationmedicine.medical_specialtymedicine.drug_classbusiness.industrymedicine.medical_treatmentPerioperativeHypoxia (medical)medicine.diseaserespiratory tract diseasesObstructive sleep apneaSedativeObstructive sleep apnea Perioperative complications Noninvasive ventilation Noninvasive positive pressure ventilation Continuous positive airway pressuremedicineContinuous positive airway pressuremedicine.symptomIntensive care medicineAdverse effectbusinessHypercapnia

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Blood pressure responsiveness to obstructive events during sleep after chronic CPAP

2003

The aim of this study was to investigate whether chronic continuous positive airway pressure (CPAP) affects blood pressure (BP) responsiveness to obstructive events occurring on the first night of CPAP withdrawal in obstructive sleep apnoea (OSA) after chronic treatment. Thirteen male subjects with severe OSA underwent nocturnal polysomnography with beatbybeat BP monitoring before treatment and after 4.9±3.4 months of home CPAP (mean daily use 5.1±1.7 h). Variations in oxyhaemoglobin saturation (Δ S a,O2), systolic (Δ P s), and diastolic (Δ P d) BP within nonrapid eye movement apnoeas and hypopnoeas were measured on a sample of pre and posttreatment events. In addition, a pretreatment s…

Pulmonary and Respiratory MedicineAdultMaleBlood pressure Continuous positive airway pressure Hypoxaemia Polysomnographymedicine.medical_treatmentPolysomnographyPositive pressureDiastoleBlood PressurePolysomnographyRisk AssessmentSensitivity and SpecificitySeverity of Illness IndexSampling StudiesPositive-Pressure RespirationmedicineHumansContinuous positive airway pressureProspective StudiesMonitoring PhysiologicProbabilitySleep disorderSleep Apnea Obstructivemedicine.diagnostic_testbusiness.industryRespiratory diseaseApneaBlood Pressure DeterminationMiddle Agedmedicine.diseasePrognosisrespiratory tract diseasesBlood pressureTreatment OutcomeAnesthesiaLinear Modelsmedicine.symptombusiness

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Recommendations for the management of patients with obstructive sleep apnoea and hypertension.

2013

This article is aimed at addressing the current state-of-the-art in epidemiology, pathophysiology, diagnostic procedures and treatment options for appropriate management of obstructive sleep apnoea (OSA) in cardiovascular (in particular hypertensive) patients, as well as for the management of cardiovascular diseases (in particular arterial hypertension) in OSA patients. The present document is the result of work performed by a panel of experts participating in the European Union COST (Cooperation in Scientific and Technological research) Action B26 on OSA, with the endorsement of the European Respiratory Society and the European Society of Hypertension. In particular, these recommendations …

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtySleep apnoea COSTMEDLINEArterial hypertension continuous positive airway pressure treatment guidelines hypertension treatment obstructive sleep apnoeaCardiologyMyocardial IschemiaBlood PressureSettore MED/10 - Malattie Dell'Apparato Respiratoriota3111Renin-Angiotensin SystemRisk FactorsEpidemiologymedicinemedia_common.cataloged_instanceHumansIn patientObesityEuropean unionIntensive care medicineStrokeLife StyleSocieties Medicalmedia_commonAgedta3126InflammationSleep Apnea Obstructivebusiness.industryRespirationSleep apneaMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREMiddle Agedmedicine.diseaseObesityEuropeStrokeBlood pressureHypertensionFemaleEndothelium VascularbusinessThe European respiratory journal

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Cardiovascular Events in Moderately to Severely Obese Obstructive Sleep Apnea Patients on Positive Airway Pressure Therapy.

2016

Background: In moderately to severely obese patients with obstructive sleep apnea (OSA), the effects of long-term positive airway pressure (PAP) treatment on cardiovascular risk are poorly defined. Purpose: To assess the effect of continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) on the occurrence of cardiovascular events in obese OSA patients. Methods: We performed a noninterventional observational study in obese OSA patients recruited between 2007 and 2010 at the Sleep Center, University of Grenoble, treated with CPAP or NIV, and followed for 5.6 year…

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_treatmentMyocardial Infarctionmacromolecular substancesComorbiditySettore MED/10 - Malattie Dell'Apparato Respiratorio030204 cardiovascular system & hematologySeverity of Illness Index03 medical and health sciences0302 clinical medicineSleep and breathingRisk FactorsSeverity of illnessPositive airway pressuremedicineMyocardial RevascularizationHumansContinuous positive airway pressureMyocardial infarctionAngina UnstableObesityAcute Coronary SyndromeStrokeAgedSleep-disordered breathing · Longitudinal studies · Continuous positive airway pressure · Noninvasive ventilation · PrognosisSleep Apnea ObstructiveContinuous Positive Airway Pressurebusiness.industryArrhythmias CardiacMiddle Agedmedicine.diseaseObesityrespiratory tract diseasesObstructive sleep apneaStroke030228 respiratory systemCardiovascular DiseasesAnesthesiaFemalebusinessRespiration; international review of thoracic diseases

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Effectiveness and safety of a new helmet CPAP configuration allowing tidal volume monitoring in patients with COVID-19.

2021

Abstract Background High generated tidal volumes (Vt) have been correlated with higher risk of self-induced lung injury and worse clinical outcome. This study aimed to evaluate the effectiveness and safety of a new helmet continuous positive airway pressure delivered (h-CPAP) configuration allowing Vt monitoring in patients affected by COVID-19. Methods This prospective observational study was performed in the respiratory intermediate care unit of University Hospital in Turin, Italy, between March 24th, and June 15th, 2020. Included patients were treated with CPAP via a single-limb intentional leak configuration by a turbine-driven ventilator, provided with a dedicated patch. Effectiveness …

Pulmonary and Respiratory MedicineLeakTidal volume monitoringmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)List of abbreviations: ARF Acute respiratory failuremedicine.medical_treatmentLung injuryTidal volumeVt Tidal volumeCPAPMedicineIn patientContinuous positive airway pressureTidal volumeHelmetCPAP Continuous positive airway pressureRICU Respiratory intermediate care unitbusiness.industryCOVID-19ICU Intensive care unitEmergency medicineHFNT High flow nasal therapyObservational studyOriginal ArticleTDVs turbine-driven ventilatorsbusinessPulmonology

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